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Therefore, results cannot be explained by light affecting depressive-like behavior through other pathways [i.e., without disturbing sleep or circadian rhythmicity, or through pathways unrelated to the SCN ( Clinical evidence supports that dysfunctions of the circadian timekeeping system are present in a variety of morbid clinical conditions, such as obesity, diabetes, hypercholesterolemia, cardiovascular diseases, and cancer (Figure 1)
Similar to the systemic circulation, within the lung, investigators have not been able to consistently demonstrate alterations of glutathione peroxidase in asthmatic subjects
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