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Both doses led to an increase in maximal respiration and ATP-linked respiration in HC cells, while mitochondrial biogenesis and oxidative phosphorylation gene expression remained unchanged, suggesting that UA specifically enhances mitochondrial respiration to improve chondrocyte metabolic function

Chromosomes contain the genes and other genetic material for an organism

The levels of most apolipoproteins and lipoproteins are regulated by various genes, which control not only the synthesis, secretion, and metabolism of apolipoproteins but also the size, number, and metabolic pathways of lipoprotein particles in the body

at low doses for treating type 2 diabetes and at high doses for weight loss, has a lot of secondary effects, including reducing systemic inflammation through a number of pathways, Lake said