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The American Association of Clinical Endocrinology's 2022 consensus statement notes that GLP-1 receptor agonists are now first-line pharmacotherapy for obesity in patients who do not have contraindications, given their dual efficacy and cardiovascular data

Once constructed, the library could be easily screened with radioactive probes to identify specific genes It did not take long for Goodman to find the gene for somatostatin in his library (Bagley)