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Aswad and Paul Greengard from cytosol of rabbit cerebellum was shown to be characterized by an unfolded, nonglobular structure based on its hydrodynamic properties (it has a Stokes radius of 31 that corresponds to an apparent molecular mass of 54 kDa, whereas sedimentation analysis showed that the actual molecular weight of this protein is 21.7 kDa), heat stability, and acid solubility ( E

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There are currently around 54 million patients with a diagnosis of dementia worldwide with incidence rates predicted to triple internationally to 152 million people by 2050 and will cost health services $2 trillion a year by 2030 as per the World Alzheimer Report 2018 [3]