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L-Arginine helps to produce nitric oxide in the body, which has several health benefits such as improved circulation, muscle growth, and exercise performance, to name a few

Moreover, the EC-associated missense Fbxw7 mutation potently accelerates EC progression in mice, particularly in the context of Pten loss or Trp53 missense mutations, suggesting a synergistic effect in driving EC tumorigenesis [36]

A 2023 review in Archives of Physiology and Biochemistry found that berberine stimulates GLP-1 secretion by modulating gut microbiota and influencing insulin signaling pathways

formal clinical proof is still catching up fast