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Description

Koo, S.I

Typically, it is only cats with very serious CKD (for example, IRIS stage four, creatinine level more than 440mmol/L) where optimal management of hyperthyroidism proves difficult, or impossible, without inducing a clinical and laboratory deterioration in renal function

However, at non-physiologic levels ROS are highly toxic and cause widespread non-specific damage to many biological systems

In addition, significant transcriptional induction of several PR genes as well as differential changes in multiple GST transcripts were observed (Sana et al., 2010)