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Whilst these findings have mainly been observed in animal models or in type 2 diabetes, their relevance to (clinical) type 1 diabetes is conceivable but, so far, largely unexplored

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A few commenters suggested alternatives to blanket penalties in public reporting, proposing the use of performance flags or annotations to highlight poor Safety of Care scores without reducing hospitals' Overall Hospital Quality Star Rating, thereby providing meaningful safety information while preserving rating comparability

GGT catalyses the breakdown of the -glutamyl bond in the substrate and generates p-nitroanilide (pNA), which is monitored kinetically by an increase in absorbance at 418 nm