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Before starting, patients should undergo baseline bloodwork including oxidative stress markers, liver and kidney function, inflammatory cytokines, and ideally genetic assessment in glutathione metabolism pathways

Recent studies have also shown that SAM can act as a therapeutic agent for treating depression, as an antidepressant in Parkinsons disease, and in endogenous and bipolar patients with depression and hypomanic symptoms (, )

International Journal of Molecular Sciences , 25(5), 2952