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Jimenez-Loygorri JI, Villarejo-Zori B, Viedma-Poyatos A, Zapata-Munoz J, Benitez-Fernandez R, Frutos-Lison MD, et al

Fact: Formulation quality and delivery technology (like liposomes) matter more than the raw weight of the ingredient, as standard forms are poorly absorbed by the gut

Reported benefits (per available research): FDA-approved, clinical-trial-supported reduction of excess visceral abdominal fat in HIV-associated lipodystrophy, the only indication with robust human RCT evidence behind it Studied in a randomized, placebo-controlled trial for possible support of executive function and cognitive performance in healthy older adults and adults with mild cognitive impairment (Baker et al., 2012) Proposed, but far less rigorously studied in healthy or bodybuilding populations, to support lean body mass and body composition changes through GH/IGF-1 axis stimulation

Additionally, they promote lymphatic transport to bypass hepatic first-pass metabolism, significantly improving bioavailability