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Both patients described herein achieved rapid remission of long-standing, antihistamine-refractory CSU shortly after starting GLP-1RA therapy (semaglutide or tirzepatide), initially prescribed for metabolic indications

In November 2023, the FDA granted approval for Zepbound (tirzepatide) for chronic weight management in adults with obesity (body mass index 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition such as hypertension, dyslipidemia, type 2 diabetes, obstructive sleep apnea, or cardiovascular disease

M., Fischer, T