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PLoS One 10 (6), e0127551

The side effect profiles at equivalent escalation points are different

However, pretreatment with 10 g/g GHK-Cu significantly increased both SOD activity and GSH levels, bringing them to values comparable to control mice

Retrograde Mitochondrial-Nuclear Signaling One interesting feature of MOTS-c biology is that MOTS-c seems to travel to the nucleus of cells under conditions of stress and alter the expression of nuclear genes that control antioxidant defences as well as metabolic programs