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We further attempted to confirm this hypothesis by knocking down GSTP1 in A2780DPP cells grown in the absence of cisplatin selection, but found that control untransfected A2780DPP cells did not retain a stable drug-resistant phenotype over the 6-week experimental period in the absence of cisplatin selection (data not shown)

Drug Metabolism Reviews, 49(1), 5683

Three participants prematurely withdrawn reported an AE related to a gastrointestinal disorder (lipase increase, nausea, constipation), a known class effect for GLP-1 agonists

Therefore, we highly recommended characterizing the genotype because is an important tool not only for HCV therapy but also for epidemiological studies