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Patients meet with providers virtually or in-person to monitor health, progress, and medication adjustments

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Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]

Overall, GLP-1 users skew Gen X, African American or Hispanic, and lower income than non-users