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In the present investigation, extreme accumulation of H 2 O 2 at MDS and SDS in the sensitive variety might be due to acceleration of the Haber-Weiss reaction that causing formation of hydroxyl radical (OH), hence, resulting in more MDA production and damage of cell membrane 8
The N-terminal domain is in aa 383, which is characterized by the structure, a tyrosine catalytic residue site (Try7) and eight G-sites binding to GSH, namely Try7, Trp8, Trp45, Lys49, Asn58, Val59, Gln71 and Ser72