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*Correspondence: Shuxin Han, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The mechanistic data cited throughout this article derive from in vitro fibroblast studies and rodent models, which limits generalizability [1]