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GLP-1 (glucagon-like peptide-1) is a peptide hormone your body produces naturally after eating

PPIs, antibiotics, NSAIDs, corticosteroids, hormone replacement therapy, hormonal birth control, diuretics, and GLP-1s (indirectly) can deplete folate

Toxicity evaluation According to a patent, "Short duration safety studies with Dihexa have uncovered no apparent toxicity

This is the same physiologic process seen when someone stops lifting weights: muscle size decreases because the stimulus is gonenot because muscle is being destroyed. Common Misconception: GLP-1 Drugs Burn Muscle Reality: Muscle loss during GLP-1associated weight loss is driven by reduced mechanical load and insufficient protein/calories , not by a toxic or catabolic drug effect. When Lean-Mass Loss Becomes True Muscle Wasting True muscle wasting is uncommon with GLP-1 therapy and is usually related to undernutrition , not the medication itself