semaglutide 50 mg skathire @jimmytrevaskis Lets await #weightloss with 50mg oral in PPL with #T2D Extent of weight loss usually greater in PPL with #obesity without #diabetes Devil will be in the details OASIS 1 trial: Oral semaglutide

95% CI: 2.11 to 3.00) for 15% weight reduction

a 5-item questionnaire relating self-reported clinical features of sarcopenia) with muscle strength testing, such as grip strength, and suggest more detailed assessment using image-derived quantification of muscle quantity/quality, and physical performance testing, are reserved for disease prognostication and research purposes [35]

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Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist consisting of 31 amino acids, structurally modified from native GLP-1 to extend its half-life through albumin binding