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This documentation must come from the prescribing provider and typically needs to specify the clinical reason for compounding, such as: Allergy to an inactive ingredient in the commercial product Need for a dose not available in commercial presentations Documented intolerance to the commercial delivery device Billing compounded tirzepatide through the pharmacy benefit uses standard pharmacy claim formats (NCPDP) with the compounding pharmacy NDC

2016 Nov;42(5):31627

Alcohol consumption and other risk factors for self-reported diabetes among middle-aged Japanese: a population-based prospective study in the JPHC study cohort I

FDA flagged both as potentially clinically relevant signals that warrant caution