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Notably, redox signaling events are significant regulators of cell death pathways, among which GSH depletion has been demonstrated to be a vital early hallmark in the progression of different cell death mechanisms [18]

In ISO-induced myocardial infarction, pretreatment with Gln maintained cardiac GSH kurtosis and antioxidant enzyme (GPX, SOD, CAT) activity at near-normal levels, thus preventing oxidative damage in the myocardium [111]

Fu J, Liu G, Yang M et al (2019) Isolation and functional analysis of squalene synthase gene in tea plant Camellia sinensis