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doi: 10.1016/0304-4165(92)90102-Z

Oxytocin is sometimes referred to as the love hormone for the boost in its endogenous production during courtship and immediately following intercourse.35 36 Those good vibes apparently extend to the treatment of anxiety and depression, at least in some research.37 The hangup here is that there isnt much research into topical oxytocin administration outside of vaginal application in menopausal and postmenopausal women, where its used to improve libido and intercourse quality.38 More research is needed to determine if topical oxytocin is truly recommendable for depression and anxiety

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