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While BMI remains the regulatory gold standard for defining study populations, the impact of the Lancet Commission Recommendationson future clinical trial endpoints in Cardiovascular, Kidney, and Metabolic Syndrome trials remains to be determined 1,2

Iilun Murphy, director de la Oficina de Medicamentos Genricos del Centro de Evaluacin e Investigacin de Medicamentos de la FDA

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Thus, targeting IL-12 or NK cells to treat endometriosis may have unexpected outcomes unless further clarity is obtained regarding their actual roles in endometriosis