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Providence, Rhode Island, Roger Williams General Hospital, Division of Genetics and Brown University, Division of Biological and Medical Sciences (Unpublished report submitted to WHO by Diamond Shamrock Corporation, Mentor, USA)

Oxygen limitation inhibits the expression of genes encoding mitochondrial respiration-related proteins and promotes the expression of proteins associated with glucose transportation and glycolysis [131, 132]

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While not FDA-approved for longevity enhancement, its used in supervised medical protocols for healthspan optimization and biological age management