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J Korean Med 33:2533 Stagos D, Spanou C, Margariti M et al (2007) Cytogenetic effects of grape extracts (Vitis vinifera) and polyphenols on mitomycin C-induced sister chromatid exchanges (SCEs) in human blood lymphocytes

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30 , 86576 e5 (2019)

However, alcohol disrupts sleep architecture (particularly REM sleep), impairs melatonin production, and increases cortisol, essentially working against everything pineal peptides are trying to achieve