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This directly complicates patient screening and enrollment, leads to substantially lower overall expected efficacy compared with patients harboring upstream genetic defects (such as POMC deficiency) [56] , and results in a low statistical success rate in large-scale trials

Peptides in Medicine Peptides have played a significant role in modern medicine for more than a century

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While pharma companies like Novartis have invested billions in drugs to treat age-related diseases and alleviate their symptoms, in the past theyve spent very little investigating the biology of ageing the biological processes and mechanisms that explain why cells, tissues, and organs gradually lose function, leading to age-related decline and disease