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The tendency for increased t 1/2 with increasing renal impairment was not considered clinically relevant, as exposure was similar between groups, and results supported once-weekly SC administration of cagrilintide

The coding sequence of full-length potential interactors was cloned into the prey vector pGADT7 and co-transformed with pGBKT7-SsCm1 SP into Y2HGold yeast cells

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