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Resources: Pillar 5: SGLT-2 inhibitors SGLT-2 inhibitors lower glucose by increasing urinary glucose excretion, reducing glucose toxicity, and often reducing insulin requirements, without directly increasing insulin

Healthcare providers may recommend several approaches including continued monitoring with more frequent follow-up, referral to mental health specialists for evaluation and management, consideration of anxiety treatment with counseling or medication if clinically indicated, or in some cases, dose adjustment or discontinuation of Zepbound if a clear temporal relationship suggests medication involvement

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Patients should be educated about recognising symptoms of hypoglycaemia, particularly if taking Mounjaro alongside other glucose-lowering medications such as insulin or sulphonylureas