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In 2019, the FDA approved bremelanotide under the brand name Vyleesi as a treatment for acquired, generalized HSDD in premenopausal women
Future multicenter studies with longer follow-up periods are needed to validate these findings and better evaluate the long-term benefits and limitations of this treatment approach
2000 Nov;48(11):1050-2
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long-acting GLP-1RAs on AMD, long-acting agents are known to be more effective in terms of glycemic control and body weight, and it has been suggested that weight-loss mediated pathways may drive the ocular benefits associated with GLP-1RA use. However, they pointed out that this study cohort was matched for hemoglobin A1c and BMI, which decreases the likelihood that the more pronounced benefit associated with long-term agents is due to these factors alone. Moreover, in obese and non-obese individuals, GLP-1 agonist therapy exhibited comparable reduced risks of dry (21% vs
