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Testicular toxicity: evaluation during drug development

10.1016/j.ecoenv.2007.11.016 18 KishorP

CBS and CSE have been reported to re-localise to mitochondria in response to hypoxia, a common feature of the tumour microenvironment, resulting in targeted H 2 S delivery that can stimulate ATP production and protect mitochondria from oxidative stress

CS-NPs, therefore, emerge as biodegradable yet robust carriers for CNS-targeted therapeutics, with all degradation products being non-toxic, non-immunogenic, and non-carcinogenic (95)