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En resumen, a partir de este grupo de pptidos se han desarrollado frmacos con efecto antihiperglucemiante que intentan obviar la rpida degradacin de las incretinas una vez secretadas y se han desarrollado otras estrategias teraputicas para evitar este deterioro de la respuesta a las incretinas: los arGLP-1, resistentes a la degradacin por DPP-4 y los iDPP-4

The path is full of hurdles

On the clinical front, an increasing number of studies in recent years have suggested favorable effects of GLP-1 RAs on erectile and sexual function, as well as on reproductive outcomes in both men and women [192]

Special Situations and Questions Lets address some common questions and special circumstances