Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for diabetes and obesity, exhibit pleiotropic effectsincluding anti-inflammatory, antioxidant, and neuroprotective propertiesthat position them as transformative candidates for ocular therapeutics
J Alzheimer's Dis 40:519529 Gu M, Owen AD, Toffa SE, Cooper JM, Dexter DT, Jenner P, Marsden CD, Schapira AH (1998) Mitochondrial function, GSH and iron in neurodegeneration and Lewy body diseases
Estos mecanismos combinados contribuyen a la capacidad del pptido para estabilizar la microcirculacin y mitigar el estrs oxidativo, lo que respalda la investigacin en modelos de inflamacin crnica, proteccin orgnica y reparacin sistmica
Microorganisms 12 (9), 1747 (2024)