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Older women are more likely to suffer from previous pathological conditions, such as obesity, high blood pressure, or insulin resistance, placing them at high risk for pregnancy complications

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Dysregulated transcription factors like peroxisome proliferators-activated receptors (PPARs) and Sterol-regulatory element binding proteins (SREBPs) affect fatty acid metabolism and regulate genes involved in spermatogenesis [226]

Valenzuela A, Aspillaga M, Vial S, Guerra R (1989)