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Monitoring and adjustment protocols should include: Weight and vital signs at each visit (initially monthly, then quarterly) Assessment of medication tolerance and adherence Evaluation of eating behaviors and physical activity Laboratory monitoring as outlined previously Reassessment of weight-related comorbidities Realistic expectations should be established through shared decision-making

STEP 4 directly compared the effect of semaglutide continuation versus semaglutide discontinuation on body weight (9)

It can be prescribed to adults or children over the age of 12

Some patients experience fewer neurological side effects with oral semaglutide because it bypasses initial subcutaneous depot effects and distributes more gradually