Regulation of g-glutamylcysteine synthetase by protein phosphorylation
PPAR can upregulate genes involved in fatty acid transport, as well as the fatty acid -oxidation process related to the mitochondria and peroxisomal, to facilitate the intake, utilization, and catabolism of fatty acid (158160), and the mechanism behind this may be an increase in both number and function of mitochondria, leading to a reduction in lipid accumulation (161163)
Ueda H, Nakai T, Konishi T, Tanaka K, Sakazaki F, Min K-S
For example, N-acetylcysteine (NAC), which has a similar mechanism of action to the supplement utilized in this study, was effective at improving irritability in children with ASD ( A nutritional supplement composed of a cysteine-rich whey protein isolate (CRWP) that serves as a potent glutathione precursor, Immunocal, is commercially available