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This crosstalk amplifies neuroinflammatory signaling and alters neurovascular integrity, contributing to blood-brain barrier disruption, glial priming, and neuronal injury 11-12

Vascular and neurodegenerative disorders in T2D may involve the same pathways such as hyperglycemia, altered insulin signaling, severe low-grade inflammation, and AGE to cause neurocognitive decline

CagriSema is a two-drug combo of semaglutide (you've heard of this one, it's the active ingredient in Wegovy and Ozempic) and cagrilintide

patients in both arms received folic acid, vitamin B12, and dexamethasone [see Dosage and Administration (2.4)]