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Despite this, GSH treatment has been sparingly investigated for mitigating the effects of air pollution exposure
For instance, depletion of mGSH results in Trx2 oxidation (Zhang et al., 2007), while hypercholesterolemic pigs with selective depletion of mGSH in heart mitochondria, exhibit decreased levels of the mitochondria-specific antioxidant enzymes such as SOD2, Trx2, and Prx3 (McCommis et al., 2011)
Munnich A, Demily C, Frugre L, Duwime C, Malan V, Barcia G, Vidal C, Throo E et al (2019) Impact of on-site clinical genetics consultations on diagnostic rate in children and young adults with autism spectrum disorder
While each peptide has established research profiles, the blend allows investigation of potential additive or synergistic effectswhether combining different repair mechanisms produces outcomes different from either peptide alone
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