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Additionally, by phosphorylating p62, mTORC1 facilitates the binding of p62 and Keap1, which causes Keap1 to degrade and NRF2 to accumulate (107)

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Cost considerations favor oral supplements : IV therapy runs $199-$400+ per session with typical protocols requiring 1-3 sessions weekly ($800-$4800+ monthly), whereas oral supplements offer a more budget-friendly option with the convenience of home administration