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Molecular targets and signaling pathways involved in the anticancer potential of IVM As mentioned above, the anticancer mechanism of IVM involves a wide range of signaling pathways such as Wnt/-catenin, Akt/mTOR, MAPK and other possible targets such as PAK1 and HSP27, as well as other mechanisms of action (Table 2 )

It could be that these comfort foods have influence via the ventral tegmental area-nucleus accumbens reward network, emphasizing the monoaminergic system to be involved as well [221]

One antioxidant in particular, glutathione, has gained a lot of attention in recent years for its impressive benefits