Their study identified senkyunolide I as a component that enters both the systemic circulation and the brain, suggesting it may serve as the key bioactive constituent underlying the anti-migraine effects of these fractions ( As principal active constituents of Apiaceae medicinal plants such as Ligusticum chuanxiong , senkyunolides have been widely investigated for their pharmacokinetics, tissue distribution, and metabolism using advanced analytical techniques and experimental models
Similar content being viewed by others Introduction Diseases linked to obesity, such as type 2 diabetes mellitus (T2DM), cancer, and cardiovascular diseases, are caused by excessive energy and fat consumption [1,2,3]
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In our previous work, we successfully detected A38, A40 and A42, total-tau (t-tau) and phosphorylated-tau (p-tau) isoforms in tear fluid 11,12
