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Individuals with this genotype may benefit from prioritizing consistent sun protection (broad-spectrum SPF, protective clothing) and supporting skin health through a diet rich in antioxidants (vitamin C, vitamin E, carotenoids like beta-carotene and astaxanthin) that help counteract UV-induced oxidative stress

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Moreover, the circadian rhythm persists despite a continuous infusion of CRH, suggesting that other factors are responsible for the modulation of ACTH pulses (176)