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This small case study showed that GSH patch in two older adults with low Glutathione levels significantly increased GSH levels within a week that persisted over three weeks

In the post-intervention network, reduced interaction density was observed between dysregulated metabolites and genes including SRM , ODC1 , and AMD1 , which are involved in polyamine biosynthesis and methylation pathways

Together, these modifications, induced by coordinated targeting of transcription factors that is currently referred to as epigenetic marks, conform to a precise code with specific time requirements to control whole gene expression 139