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Supplemental Table S3, summarizes candidate surrogates for assessing histological response to MASH pharmacotherapy

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For constipation, which is also common with Wegovy, bulk-forming laxatives like ispaghula husk or osmotic laxatives such as macrogol are generally safe and effective

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The broader competitive context including Novo Nordisk's amycretin program and Foundayo (orforglipron) is covered in our 2026 oral GLP-1 overview

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Why Scar Age Matters Clinical research reveals an important finding: scar age affects treatment response

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