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While these drugs can be very effective, the first week is often a time of adjustment as your body gets used to the medication

Studies such as the LEADER trial (liraglutide), SUSTAIN-6 (semaglutide), and REWIND (dulaglutide) have shown reductions in major adverse cardiovascular events, including heart attack and stroke, in people with type 2 diabetes and established cardiovascular disease or high cardiovascular risk

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For patients taking oral semaglutide (Rybelsus), specific administration instructions must be followed: take with no more than 4 ounces of plain water on an empty stomach, at least 30 minutes before eating, drinking, or taking other oral medications