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The obesity Phase 3 studies and the first topline readout The obesity backbone includes 76-week efficacy-and-safety trials in adults with overweight or obesity without type 2 diabetes (SYNCHRONIZE-1, NCT06066515) and with type 2 diabetes (SYNCHRONIZE-2, NCT06066528), plus region-specific studies

DOI.org (Crossref) , International Archives of Allergy and Applied Immunology , vol

Semaglutide is thought to be a more potent therapy than liraglutide or dulaglutide [21], so semaglutide therapy may increase the intensity of delayed gastric emptying and the incidence of GSEs

References Retatrutide (LY3437943) Phase 3 development programme (Eli Lilly), pre-publication as of 2026 no journal paper available