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The Goals I Focus on in Peri-Operative Optimisation Before I talk about specific compounds, I want to be clear about the goals I think about for every patient I prepare for surgery
By blocking NNMT, 5-Amino-1MQ has been studied for its role in conserving nicotinamide for NAD production while maintaining SAM
Many notice reduced pain within 1-3 weeks, with peak benefits at 3-6 months as tissues regenerate
Fatigue is listed as a common adverse reaction (occurring in 5% of patients) in the FDA prescribing information for both Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), and occurred more frequently than with placebo in clinical trials
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