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Major milestones of butyrate action and results from key therapeutic trials are summarized in Table 1

This requires careful consideration of dosing equivalency, adherence, and therapeutic goals, Dr

Clinical trials demonstrate sustained 210 fold increases in GH and 1.53 fold increases in IGF-1, with elevated IGF-1 persisting for up to 28 days after multiple doses [3]

There was insignificant heterogeneity in all three doses: P = 0.47, I 2 = 0%, P = 0.26, I 2 = 20%, and P = 1.00, I 2 = 0%, respectively ( Table 3 , Supplemental Figure S4)