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10.2337/dc13-2761 55 NauckM

Mechanistically, BPC-157 appears to function through nitric oxide-mediated vasodilation, angiogenic factor regulation, and recruitment of fibroblasts and endothelial progenitor cells 1-3

TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition

In 2024, the FDA expanded the label to include reducing the risk of major cardiovascular events in adults with established cardiovascular disease and overweight or obesity based on the SELECT trial, which randomized 17,604 patients and showed a 20% reduction in major adverse cardiovascular events over a mean 40 months