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Results Tibetan-specific M9a haplogroup enhances mitochondrial function under hypoxia Our previous studies, as well as those of others, have consistently demonstrated that the M9a haplogroup is the most prevalent mitochondrial haplogroup among Tibetans [16, 17]

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This stepwise escalation principle mirrors the approach used for licensed medicines such as semaglutide (Wegovy, UK SmPC available via the electronic Medicines Compendium) and tirzepatide (Mounjaro, UK SmPC available via the electronic Medicines Compendium), both of which are approved by the MHRA and recommended within relevant NICE guidance for specific indications