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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for managing type 2 diabetes mellitus (under brand names Ozempic and Rybelsus) and chronic weight management (Wegovy)
Although these findings suggest a potential advantage of tirzepatide in populations vulnerable to sarcopenia, the study was limited by its single-center retrospective design, small sample size, and restricted control of confounding, and, therefore, requires confirmation in prospective studies
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