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Description

Retatrutide is an investigational triple receptor agonist that also targets the glucagon receptor

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Further studies will be needed to specifically determine which neuronal subtypes are affected

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INSR is a transmembrane receptor tyrosine kinase organized as an 2 2 tetramer, with subunits located extracellularly for ligand binding and subunits spanning the membrane and harboring the tyrosine kinase domain (70, 71)

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10.1016/j.vph.2018.05.003 81

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