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While the second-order rate constants of PfGrx C88S and PfGrx C32S/C88S for GSSG are one order of magnitude higher than for bulky roGFP2(SSG), the rate constant for the glutathionylation of PfGrx C32S/C88S by GSSG is twice that with GSSCys (Table 1) 14

Consequently, folic acid averages of around 1025% in the flour are necessary to compensate for the losses during baking and to achieve the required folic acid values in fortified bakery products 302,426,428,429

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